Antonyms for the phrase "settle one's nerves" are those that imply agitation, anxiety, or restlessness. Among the possible antonyms are "frazzle," "unsettle," "discompose," "jitter," "agitate," "fluster," "disturb," "unhinge," and "disorder." Each word suggests a state of unease that can be physical or mental, resulting in discomfort or distress. Specific circumstances can cause such agitation, such as the anticipation of a significant event, dealing with unfamiliar situations, or unexpected changes. In each case, the individual's nervous system reacts to stimuli, often resulting in a lack of peace of mind.
